Four games kick off at 7.30pm, and two at 8.15pm
There are six Premier League matches tonight.
Four games kick off at 7.30, with second placed Liverpool away to Sheffield United.
Republic of Ireland international Caoimhin Kelleher will start in goal for the Reds.
In the other games which begin at that time, Brighton play Brentford, Crystal Palace take on Bournemouth and Fulham meet Nottingham Forest.
There are two games which begin at 8.15.
Champions Manchester City go to Aston Villa, who are bidding for a 14th straight home league win.
Rodri is suspended for City.
At Old Trafford, Manchester United take on Chelsea.
United are in the headlines over stories of dressing room disquiet with manager Erik ten Hag.
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