Scott Parker's Fulham side have made an immediate return to the Championship.
The Cottagers were beaten 2-0 at Craven Cottage by Burnley last night who, in turn, secured their Premier League safety.
Goals from Ashley Westwood and Chris Wood before the half time break claimed the victory for Sean Dyche's men.
Fulham now join West Brom and Sheffield United in being relegated to the Championship.
Meanwhile, Manchester United will look to keep the title race going for another game tonight.
United host Leicester City, who will look to get their bid for Champions League qualification back on track.
A win for the Foxes would see Manchester City crowned champions.
It's United's first game at Old Trafford since their match with Liverpool was called off.
Kick off is 6pm.
That game is followed by the meeting of Southampton and Crystal Palace - it's an 8.15 start at St. Mary's.
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